Alzheimer Disease
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Free-water: A promising structural biomarker for cognitive decline in aging and mild cognitive impairment
Sathe, Aditi; Yang, Yisu; Schilling, Kurt G.; Shashikumar, Niranjana; Moore, Elizabeth; Dumitrescu, Logan; Pechman, Kimberly R.; Landman, Bennett A.; Gifford, Katherine A.; Hohman, Timothy J.; Jefferson, Angela L.; Archer, Derek B. 鈥淔ree-water: A promising structural biomarker for cognitive decline in aging and mild cognitive impairment.鈥 Imaging… Read MoreJune 20, 2025
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The effect of Alzheimer’s disease genetic factors on limbic white matter microstructure
Lorenz, Anna; Sathe, Aditi; Zaras, Dimitrios; Yang, Yisu; Durant, Alaina; Kim, Michael E.; Gao, Chenyu; Newlin, Nancy R.; Ramadass, Karthik; Kanakaraj, Praitayini; Khairi, Nazirah Mohd; Li, Zhiyuan; Yao, Tianyuan; Huo, Yuankai; Dumitrescu, Logan; Shashikumar, Niranjana; Pechman, Kimberly R.; Jackson, Trevor Bryan; Workmeister, Abigail W.; Risacher, Shannon L.; Beason-Held, Lori… Read MoreMay 21, 2025
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Learning disentangled representations to harmonize connectome network measures
Newlin, Nancy R.; Kim, Michael E.; Kanakaraj, Praitayini; Pechman, Kimberly; Shashikumar, Niranjana; Moore, Elizabeth; Archer, Derek; Hohman, Timothy; Jefferson, Angela; Moyer, Daniel; Landman, Bennett A. “Learning disentangled representations to harmonize connectome network measures.” Journal of Medical Imaging, vol. 12, no. 1, 2025, 14004, https://doi.org/10.1117/1.JMI.12.1.014004… Read MoreMarch 24, 2025
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Longitudinal patterns of brain aging and neurodegeneration among older adults with dual decline in memory and gait
Tian, Qu; Greig, Erin E.; Walker, Keenan A.; Duggan, Michael R.; Yang, Zhijian; Moghekar, Abhay; Landman, Bennett A.; Davatzikos, Christos; Resnick, Susan M.; Ferrucci, Luigi. “Longitudinal patterns of brain aging and neurodegeneration among older adults with dual decline in memory and gait.” Alzheimer’s & dementia : the… Read MoreMarch 24, 2025
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Association of Plasma Biomarkers of Alzheimer Disease and Neurodegeneration With Longitudinal Intra-Network Functional Brain Connectivity
Dark, Heather E.; Shafer, Andrea T.; Cordon, Jenifer; An, Yang; Lewis, Alexandria; Moghekar, Abhay; Landman, Bennett; Resnick, Susan M.; Walker, Keenan A. “Association of Plasma Biomarkers of Alzheimer Disease and Neurodegeneration With Longitudinal Intra-Network Functional Brain Connectivity.” Neurology, vol. 104, no. 4, 2025, e210271,… Read MoreFebruary 24, 2025
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Sex and APOE 蔚4 allele differences in longitudinal white matter microstructure in multiple cohorts of aging and Alzheimer’s disease
Peterson, Amalia; Sathe, Aditi; Zaras, Dimitrios; Yang, Yisu; Durant, Alaina; Deters, Kacie D.; Shashikumar, Niranjana; Pechman, Kimberly R.; Kim, Michael E.; Gao, Chenyu; Mohd Khairi, Nazirah; Li, Zhiyuan; Yao, Tianyuan; Huo, Yuankai; Dumitrescu, Logan; Gifford, Katherine A.; Wilson, Jo Ellen; Cambronero, Francis E.; Risacher, Shannon L.; Beason-Held, Lori L.;… Read MoreJanuary 28, 2025
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Higher skeletal muscle mitochondrial oxidative capacity is associated with preserved brain structure up to over a decade
Tian, Qu; Greig, Erin E.; Davatzikos, Christos; Landman, Bennett A.; Resnick, Susan M.; Ferrucci, Luigi. “Higher skeletal muscle mitochondrial oxidative capacity is associated with preserved brain structure up to over a decade.”聽Nature Communications, vol. 15, no. 1, 2024, 10786,聽https://doi.org/10.1038/s41467-024-55009-z.聽… Read MoreJanuary 28, 2025
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Plasma ADRD biomarkers predict longitudinal declines in intra-network functional brain connectivity, and baseline functional connectivity predicts longitudinal cognition
Dark, Heather E.; Shafer, Andrea T.; Cordon, Jenifer; An, Yang; Lewis, Alexandria; Moghekar, Abhay; Landman, Bennett A.; Resnick, Susan M.; Walker, Keenan A. “Plasma ADRD biomarkers predict longitudinal declines in intra-network functional brain connectivity, and baseline functional connectivity predicts longitudinal cognition.”聽Alzheimer’s and Dementia, vol. Read MoreJanuary 28, 2025
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Reductions in the white鈥揼ray functional connectome in preclinical Alzheimer’s disease and their associations with amyloid and cognition
Xu, L.; Zhao, Y.; Choi, S.; Li, M.; Schilling, K.G.; Zu, Z.; Rogers, B.P.; Ding, Z.; Anderson, A.W.; Landman, B.A.; Gore, J.C.; Gao, Y. “Reductions in the white鈥揼ray functional connectome in preclinical Alzheimer’s disease and their associations with amyloid and cognition.” Alzheimer’s and Dementia, 2024,… Read MoreNovember 21, 2024
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Characterizing patterns of diffusion tensor imaging variance in aging brains
Gao, Chenyu, Yang, Qi, Kim, Michael E., Khairi, Nazirah Mohd, Cai, Leon Y., Newlin, Nancy R., Kanakaraj, Praitayini, Remedios, Lucas W., Krishnan, Aravind R., Yu, Xin, Yao, Tianyuan, & Zhang, Panpan. (2024). Characterizing patterns of diffusion tensor imaging variance in aging brains. Journal of Medical Imaging, 11(4), 044007. Read MoreSeptember 22, 2024